Sildenafil 100mg - The Blockbuster Drug Molecule

Erectile Dysfunction is also known as impotence which is the persist inability in men to get a firm and strong erection for a long period of time during intercourse sessions. Sildenafil 100mg ( http://www.samrx.com/buy-sildenafil-citrate.aspx ) is the oral drug approved by FDA for treating erectile dysfunction. It has found to be the most effective for the treatment of impotence in men.

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About Erectile Dysfunction
• Erectile Dysfunction (ED) is a male sexual disorder in which a man is not able to
obtain a firm and maintain a strong penile erection for long period of time during
sexual activity
• Several treatment options are available for treating ED
• Sildenafil is considered the gold standard for treating erectile dysfunction
About Sildenafil 100mg
• Sildenafil was the first drug to be approved by FDA in the year 1998 for treating
erectile dysfunction
• It was a blockbuster drug molecule
• It is a potent and selective PDE-5 inhibitor
• It is an oral pill to be taken as and when required
Mechanism of Action
• Sildenafil 100mg enters the bloodstream and inhibits PDE-5 enzyme present in abundance inside
the penile region
• The inhibitory action increases the concentration of cGMP
• The increased concentration of cGMP relaxes the smooth muscles and dilates the blood vessels
inside the penile region
• The dilated blood vessels improve the blood flow, which in turn results in strong and firm penile
erection
Onset of Action and Duration of Effect
• Onset of action- 30 to 60 minutes after oral administration
• Duration of effect- four hours on an average
Things to avoid
• Nitrate drugs
• Blood pressure lowering medicines
• Fatty meals
• Grapefruit
• Alcohol
Common Adverse Effects
The following side effects of Sildenafil 100mg subside after the drug eliminates
from the body
• Nausea and Vomiting
• Nasal congestion
• Abdominal discomfort
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http://www.samrx.com/buy-sildenafil-citrate.aspx

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