Sildenafil Citrate - A Blockbuster Drug Molecule

Sildenafil citrate is a first oral drug approved for treatment of ED in men. It was a block buster drug molecule. Since its approval in the year 1998 by the FDA, millions of prescription are written for Sildenafil Citrate ( ).

About Sildenafil Citrate
• Sildenafil Citrate was approved by FDA for treatment of erectile dysfunction in
men in the year 1998
• The discovery of Sildenafil Citrate was a breakthrough in the field of sexual
• It belongs to pharmacological class of drugs known as PDE-5 inhibitors
Onset of action and Duration of effect
• The action of Sildenafil Citrate starts within 30 to 60 minutes
• The action lasts for period of four hours
Action mechanism
Sildenafil citrate
inhibits the PDE-5
This increase the
blood supply to the
penile organ
The increase in the
blood supply to the
penile organ produces
firm and strong penile
Dose and dosage instructions
• Sildenafil Citrate is available in strengths of 25mg, 50mg and 100mg
• The 100 mg dose of Sildenafil Citrate is the most effective dose
• Consume Sildenafil Citrate at least 30 minutes before sexual intercourse
• Take it only when required
• Do not repeat the dose in period of 24 hours
Common side effects
• Nasal congestion
• Abdominal discomfort
• Flushing
• Headache
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