The 2 Basic Principles in Natural Health 健康的两大基本要素 1. Feeding and nourishing the body systems 给身体提供充裕的营养 食物 营养 Food Nutrients 2. Cleansing and removing toxins from the body 将废物/有害物质排出体外 Getting Started Building a Healthy Foundation Isotonix® Daily Essentials Isotonix OPC-3® Isotonix Multivitamin Isotonix Activated B-Complex Isotonix Calcium Plus Isotonix ® OPC-3 The Gold Standard For Antioxidants Isotonix OPC-3® FEATURED INGREDIENT Pine Bark Extract (Pycnogenol®) Basic Properties Powerful Antioxidant Anti-inflammatory Activity Cardiovascular Health Skin Health Vasodilation and Circulation Isotonix® Multivitamin 100% of essential vitamins needed for proper nutritional balance. Vitamins serve as cofactors and coenzymes for proper functioning of enzymes/metabolic reactions (required components). Minerals are key co-factors for metabolic processes (required components). Isotonix® Multivitamin Available without iron Exceeds 100% DV for many important nutrients including: Vitamins A, C, D and E B Vitamins Zinc Selenium Copper Chromium Potassium And more! Isotonix® Calcium Plus Calcium is essential for maintaining all aspects of health: Heart Health Bone Health Teeth and Gums Nerve Conduction Hormone Secretion Blood Clotting Body Weight Immunity Does not contain excessive calcium per serving (can only absorb ~400 mg at a time). The Need for B Vitamins B-vitamins are naturally depleted by: • Alcohol • Sugar • Coffee • Stress Isotonix® Advanced B-Complex Supports metabolism Promotes nervous system and immune function Decreases stress Increases energy Supports heart health Isotonix® Daily Essentials Kit Contains Isotonix OPC-3, Multivitamin, Advanced BComplex and Calcium Plus Provides Vitamins and Minerals Heart Health Immunity Energy and Mood Stress Management Less than SG$5 per day! Save over SG$70 when you purchase the kit! What Else? Omega 3 Adults and children Probiotics Fiber Energy Greens Immunity Aloe Good Fats & Bad Fats Good [fish, nuts, seeds, coconut] - Promotes overall cardiovascular health - Helps maintain normal blood flow - Helps maintain normal blood pressure levels Bad [hydrogenated or trans fats] Constricts arteries Makes blood sticky Diminishes arterial health 3 Types of Dietary Fats Saturated fats (animal products) Monounsaturated fats are typically the best oils for cooking (olive oil has a higher oxidation threshold – resists hydrogen-ation or saturation) Polyunsaturated fats (nuts, seeds, sunflower, safflower and corn oils) **includes essential omega-3 fatty acids** Omega 3 Fatty Acids Two main types: - Long Chain FA including EPA & DHA (Eicosapentanoic Acid & Docosahexanoic Acid) Plentiful in cold water fish and shellfish - Short Chain FA including ALA (Alpha-Linolenic Acid) Found in plants such as flaxseed Fatty Acids DHA Fatty Acids Saturated Unsaturated ○ Monounsaturated Olive Oil ○ Polyunsaturated Omega-3s and Omega 6s (EFA’s) Trans-fatty acids ○ Hydrogenation EPA Importance of omega-3s Americans are NOT consuming as much fish as in the past and we eat corn fed beef Ratio of Omega 6 to Omega 3 should be 2:1 (per Am J Clin Nutr, 1999). Average American ratio is 20:1 (per Am J Clin Nutr, 2000) Need to ↓Omega 6’s (corn, sunflower oil) Good to ↑Omega 3’s (fish, shrimp) AHA Scientific Statement: Fish Consumption, Fish Oil, Omega-3 FA’s & CVD Kris-Etherton et al, Circulation (2002)106:2747-2757 Strongly encourages increased Ω-3 consumption Singles out EPA & DHA from fish as best for heart health Sets out recommended daily intakes of ~1 g of EPA + DHA for people at risk of CVD and 2-4 g for lowering triglycerides Recognizes fish oil supplements as a safe, effective alternative to eating fish for people who don’t like it or who can’t consume enough to reach effective intakes of EPA + DHA Stresses the importance of safe, high-quality supplements Sources of EPA + DHA [Target amounts: 1 or 3 g per day] Salmon 1.1g per 3 oz serving $6.99/lb at a local grocery store (8 oz = 3 g DHA + EPA) Canned tuna provides 0.36 g per 3 oz serving $1.00 per 6 oz can this week (25 oz = 3 g DHA + EPA = 4+ cans Primary Benefits of Hearth Health™ Essential Omega III Fish Oil Helps maintain: normal cholesterol levels, normal blood pressure levels, normal blood flow, normal triglyceride levels, healthy levels of c-reactive protein Promotes: overall cardiovascular health, a healthy complexion, healthy eye lubrication, normal tear production, healthy blood flow to the eye Helps enhance mood and may help to retain low-light visual acuity What Makes an Omega Supplement High Quality? High purity – small cold water fish from deep depths and molecularlly distilled to remove impurities Want the oil to be 50%+ EPA and DHA Want the ratio of EPA:DHA to be 3:2 Contain Vit E (d-α-Tocopherol) to ensure freshness Quality of Hearth Health™ Essential Omega III Fish Oil Made from sardines and anchovies harvested off the coast of Peru Each batch is hand selected and must pass more than 200 quality checks during production Oil is tested twice (manufacturer and independent lab) for PCB’s, mercury, lead and other heavy metals. The 2 Basic Principles in Natural Health 健康的两大基本要素 1. Feeding and nourishing the body systems 给身体提供充裕的营养 食物 营养 Food Nutrients 2. Cleansing and removing toxins from the body 将废物/有害物质排出体外 Digestion: Feeding and Nourishing the Body Systems 消化：为我们的身体提供营养 第一步：the oral cavity 第二步：, the stomach: digest foods to Isotonic Liquid State, or CHYME。 第三步：the small intestine 唾液腺 肝脏 胆 胰脏 胃 大肠 第四步：the colon, 每天2-3次 小肠 消化酶 (Digestive Enzymes) 什么是酶 (Enzymes)? 酶是催化体内生化反应的蛋白质, 是我们身体里的动力。 酶具有高度的特异性, 只在一定的pH值和温度范围内 有活性。 酶的种类 - 新陳代謝酶: 在细胞内工作 - 消化酶: 在消化系统的细胞外工作, 把食物中的大分子 分解成小分子。 Digestive Enzymes 消化酶的來源: - 生鮮食物: 食物经过冷冻、高温、福射、微波等处理，其中的酶的 活性和结构就完全被破坏掉。我们吃进去的绝大多数食 物是不含酶的。 - 体內产生 : 唾液腺、胃、小肠、胰脏。 Digestive enzymes are classified based on their target substrates: proteases and peptidases split proteins into small peptides and amino acids. lipases split fat into three fatty acids and a glycerol molecule. amylases split carbohydrates such as starch and sugars into simple sugars such as glucose. Early Signs of Enzyme Deficiency 缺乏消化酶的早期症狀 Digestive 消化方面 Others 其他方面 过敏 Allergies 烧灼感 Heartburn 頭疼 Headaches 气 Gas 胃痛 Stomach Aches 腹脹 Bloating 腹瀉 Diarrhea 打嗝 Belching 便祕 Constipation 慢性疲勞 Chronic Fatigue 酵母感染 Yeast Infections 營 養不良Nutritional Deficiencies Isotonix Digestive Enzyme With Probiotics • Basic 基本的: Amylase 淀粉酶 Specialty 特殊的: Cellulase纤维酶 Protease 蛋白酶 Lipase 脂肪酶 Lactase 乳糖酶 Maltase 麥芽糖酶 Sucrase 蔗糖酶 Curcumin Extreme™ Curcumin comes from Turmeric Curcumin’s Healthful Benefits Promotes normal activity of NF-kappaB Promotes normal cell cycle activity, normal cellular regeneration Helps to maintain neurological health as we age Studies Show Curcumin Promotes Normal Activity of NFKB Activation S. Shishodia et al. Curcumin down-regulates cigarette smokeinduced NF-kB activation through inhibition of IkBα kinase in human lung epithelial cells: correlation with suppression of COX2, MMP-9 and cyclin D1. Carginogenisis (2003) 24(7): 1269-1279 B.B. Agarwal et al. Curcumin suppresses the paclitaxel-induced nuclear factor-kB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin Cancer Res 2005;11(20) 7490-7498 Nuclear factor-kappa B A protein complex involved in supporting normal cellular responses to stress (such as free radical attack). NF-κB plays a key role in regulating the immune and inflammatory responses. Inadequate regulation of NF-κB has been linked to problems in joint health, digestive health and respiratory health. Importance of Apoptosis Curcumin has been found to promote normal cell cycle activity and promote apoptosis in unhealthy cells. H.S. Samaha et al. Modulation of Apoptosis by Sulindac, Curcumin...:Apoptotic Index as a Biomarker in Colon Cancer Chemoprevention and Promotion. Cancer Res 1997;57:13011-1305 Curcumin Supports Cognitive Health Normal inflammatory response Metal Chellation Curcumin Antioxidant Effects Ann Indian Acad Neurol. 2008 Jan-Mar; 11(1): 13-19 Binds to amylora plaques Curcumin Protects Neurological Health Age-related cognitive decline is related to macrophage activity being suppressed. Curcumin helps support normal macrophage activity. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):1284954. Curcumin Extreme™ Curcumin (BCM-95®): 400 mg Broccoli Seed Extract (6% Glucosinolates): 167 mg Selenium (Selenomethionine): 100 mcg Curcumin: The BCM-95® Difference Curcumin: The BCM-95® Difference Broccoli Seed Extract (6% Glucosinolates) Promotes the normal production of detoxification enzymes Helps maintain healthy glutathione levels Promotes apoptosis in unhealthy cells Promotes a strong immune system by: Supporting normal total white blood cell count Supporting normal phagocytic activity -Thejass, P. and Kuttan, G. Immunomodulatory activity of sulforaphane, a naturally occuring isothiocyanate from broccoli (Brassica oleracea). Phytomedicine. 14: 538-545, 2006. Glucosinolates Found in cruciferous vegetables. An enzyme converts it to isothiocyanates and indoles. Indole-3 carbinol promotes normal phase I and II detoxification reactions. What is “detoxification?” Carried out by enzymes produced from the information stored within our genes. Phase I: Enzymes are called “activators.” Phase II: Enzymes called “excretors.” Indole-3 carbinol promotes the normal activity of these enzymes. M.L. Clapper et al. Preclinical and Clinical Evaluation of Broccoli Supplements as Inducers of Glutathione S-Transferase Activity. Clin Cancer Res 1997; Vol 3, 25-30 Conclusion There is no finer health support product than Curcumin Extreme™. It plays a powerful role in supporting immune function, liver function, and normal cell regeneration. The all-inone supplement. Ultimate Aloe with Activated, Stable Polysaccharides Cultivating Aloe vera Source of Ultimate Aloe™ Aloe vera is grown in Texas and Mexico. Quickly moved to processing plant. Leaves are sanitized in three-stage process. Damaged leaves are removed before processing. Ultimate Aloe™ Production Produced under ultra-sanitary conditions Employees go through sanitation every time work area entered. Entire area undergoes wash down each night. Novel proprietary method enabling the dehydration of aloe while maintaining flavor, color and nutrients. Patented Process Not Only Retains, But Actually Enhances, Aloe vera’s Biological Activity. Ultimate Aloe™ Juice Zhihua Qiu, Ken Jones: Planta Medica 66, 1-5, 2000 A processing method that retains and enhances the biological activity of native aloe, resulting in a patented processing method. Immune Restoration 100% 75% 75% 50% 25% 25% 15% 6% 0% 5-10 10-50 50-200 200-2000 Polysaccharide MW (kDa) The patented MAP process: patent # 6,133,440 & 6,436,679 “Aloe as Nature Intended.” Market America Pioneers Nutritional Innovation Ultimate Aloe™ Powder retains the quality of the naturally occurring nutrients found in fresh Aloe juice through a proprietary process called TotalAloe™ extraction. And packages it in convenient, travelsize packets! TotalAloe™ Full Spectrum Extraction Process Retains over 200 biologically active components of the Aloe vera plant, including vitamins, minerals, amino acids, enzymes and polysaccharides. Isolates and concentrates the most active polysaccharides that support proper immune system function and normal digestion. TotalAloe™ and Immune Function A placebo controlled study of 75 healthy adults for 30 days, showed those taking TotalAloe™ demonstrated a 16% increase in immune system function. TotalAloe™ raised white blood cell counts to an optimal, protective level. Ultimate Aloe™ Powder Advantages All the benefits of Ultimate Aloe™ juice at 1/10th the weight. Sixteen one-serving sachets per multipack. Enjoy Ultimate Aloe™ anywhere, anytime. Preservative free. All natural flavors and colors. Ultimate Aloe™ is Certified Tested and certified by an independent laboratory for aloe content and truth in labeling. Facilities and production process audited. 1- Enhances Vitamin Bioavailability Adults 40-80 yrs given vitamins C and B12 with aloe extract. Plasma ORAC increased significantly. Plasma vitamin C and B12 levels increased significantly. The FASEB Journal 2007;21:232.6 Enhances Vitamin Bioavailability Subjects 21-42 yrs given vitamins C and E with aloe. Aloe slowed down and improved absorption. Phytomedicine 12 (2005) 760-765 2- Source of trace minerals Iron, Copper, Calcium, Zinc, Chromium, Manganese, Potassium, Sodium, Magnesium Source: Biological Trace Element Research Vol. 108, 2005 pp. 185195 NOTE: Minerals content varies depending upon growing conditions and soil. 3- Promotes normal inflammatory response Salicylic acid blocks the production of prostaglandins. Aloe also provides phytosterols that work as anti-inflammatory agents. 4- Aids in the maintenance of normal blood sugar levels 5,000 patients with heart disease were studied over a five-year period. Out of 5,000 patients, 3,167 were diabetics Took 100g Aloe gel twice a day 94% of the patients’ blood sugar levels returned to normal Phytomedicine. 3, 3:245-248, 1996. 5- Improves Skin Appearance Women over the age of 45 given aloe supplementation for 90 days. Collagen production increased throughout the dermis. Significantly improved appearance of wrinkles and elasticity. Attributed to polysaccharides modulating repairs to DNA damage. Ann Dermatol (Seoul) Vol. 21, No. 1, 2009 pp 6-11 6- Promotes healthy digestion Provides natural plant enzymes to break down food. Alkaline Phosphatase (proteins) Amylase (starch) Carboxypeptidase (proteins) Catalase (hydrogen peroxide) Cellulase (cellulose) Lipase (water insoluble lipids) Peroxidase (hydrogen peroxide) 7- Promotes normal bowel function Gastrointestinal health depends upon: Diet, genetics, stress, alcohol use, gut bacteria, presence of pathogenic organisms and inflammation. 8- Supports Gut Flora 9- Promotes Healthy Immune System Response Beta-glucomannans have protective properties. Increases collagen synthesis. Supports wound healing. Mol Cell Biochem. 1998;181:71-6 J Altern Complement Med. 1996;2:271-7 Aloe’s Diverse Properties Aloe polysaccharides promotes normal inflammatory response. Buffers GI tract, reducing acid damage. Promotes mucus secretion, protecting and lubricating GI tract. Helps stimulate growth of epithelium cells. Supports the activity of macrophages, natural killer cells and monocytes. 10- Quality Promotes customer satisfaction and sales Standardized ingredients ensures that the performance of finished goods are consistent, achieving the desired results. Activaloe™ and TotalAloe™ provide a specific polysaccharide molecular weight profile a patented process. shown to enhance bioactivity.