Improving Stroke Prevention in Patients With Atrial Fibrillation

Improving Stroke Prevention in
Patients With Atrial Fibrillation
Disclosures (cont.)
• This presentation will not include any
non-FDA approved or investigational uses
of products or medical devices.
Learning Objectives
Atrial Fibrillation (AF):
Incidence and Consequences
Projected Number of Persons With AF
in the US: 2000 to 2050
AF and Stroke
Greater Risk of Death and Recurrence
With AF Strokes
Disability vs Age Group in Those With
Acute Ischemic Stroke (AIS) vs AF-AIS
Assessing Benefits and Risks
Case 1
CHADS2 Index: A Validated Classification
Scheme/Tool for Stroke Risk
Weakness of CHADS2
The CHA2DS2-VASc Index
Which to Use?
Case 2
ACC/AHA/ESC Guidelines
Risk Stratification and Anticoagulation
Underuse of Anticoagulants in AF
Barriers to Anticoagulant Use
Barriers to Anticoagulation?
Bleeding Risk
Bleeding Risk: The Reality
Anticoagulation in Patients at Risk of Falls:
“Physicians’ Fears Are Often Unfounded”
Assessing Bleeding Risk: HAS-BLED
Reducing Bleeding Risk
Decision Support
Decision Support
Worksheet (cont.)
The Patient: Decision Making and
Patient Preferences
Patient vs Physician Perspectives
on Anticoagulation
Explaining Risk to Patients:
Numerous Tools Available
Patient Knowledge About Warfarin
Patient Adherence to Warfarin
Risk Factors for Warfarin Nonadherence
Improving Patient Adherence
to Anticoagulants
Which Antithrombotic Therapy?
Generic/Trade Name Guide for Drugs
Mentioned in Presentation
Features of Available Anticoagulants
Warfarin and Novel Anticoagulant
Mechanisms of Action
Choosing an Anticoagulant
Question Check
Clopidogrel and/or Aspirin?
ACC/AHA/ESC Guidelines:
Warfarin vs Aspirin
Warfarin: The Gold Standard
Currently Available Oral Anticoagulants
Clinical Trial Data
Limitations/Concerns With
Available Anticoagulants
Visit for a
Medication Chart (Keyword: chart)
ACC/AHA/ESC Guidelines:
Managing Through Medical Procedures
to Prevent Thrombosis
Drug-Specific Guidelines for Managing
Through Medical Procedures
When to Switch From Warfarin
Remain With Warfarin if …
Switching From Warfarin: How?
Visit for Tools,
Handouts, Calculators, and More
Periprocedural Anticoagulation
Algorithm on
(Keyword: periprocedural)
Decision Tool to Use With Patients on (Keyword: decision)
TEAM-A Town Hall on

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