Leprosy By Christine Kim Leprosy is a chronic, infectious disease that damages the skin, peripheral nerves, and mucous membranes of the mouth, throat, and eyes. There are two forms of leprosy. Tuberculoid There are two forms of leprosy. Lepramatous In 1878, Gerhard Henrik Armauer Hansen identified Mycobacterium leprae as the cause of leprosy. Leprosy was recognized in ancient China, Egypt, and India. Leprosy is hard to transmit but when transmitted it is spread by respiratory droplets. Leprosy begins as an infection in the nerve endings and spreads gradually. There are a number of symptoms: There are a number of symptoms: • Skin lesions • Muscle weakness • Numbness in hands, arms, feet, legs How does M. leprae infect our cells? Multidrug Therapy is used to treat leprosy. This involves a a combination of the antibiotics dapsone, rifampin, and clofazimine. How can we prevent the spread of leprosy? WHO’s World Health Association passed a resolution in 1991 to eliminate leprosy by the year 2000. Elimination = 1 case per 10,000 persons. The target was achieved! Prevalence of Leprosy in the year 2010 There is no official, nationally accepted vaccine for leprosy. However, there is a significant amount of research being done on the subject. Works Consulted • • • • • • • • • • • • • • Brand, Margaret. "Eye Complications in Leprosy." Stanford.edu. Stanford University, n.d. Web. 10 Nov. 2012. <http://www.stanford.edu/class/humbio103/ParaSites2006/Leprosy/snsx_files/image026.jpg>. Cherath, Lata; Frey, Rebecca. “Leprosy.” Gale Encyclopedia of Medicine, 3rd ed.. 2006. Encyclopedia.com. 15 Nov. 2012 <http://www.encyclopedia.com>. "Gerhard Henrik Armauer Hansen." Wikipedia. Media Wiki, n.d. Web. 10 Nov. 2012. <http://upload.wikimedia.org/wikipedia/commons/5/53/Gerhard_Armauer_Hansen.jpg>. Greer, Alex. "Mycobacterium Leprae." Bio.davidson.edu. Alex Greer, 2007. Web. 10 Nov. 2012. <http://www.bio.davidson.edu/people/sosarafova/Assets/Bio307/algreer/lifecycle.html>. Harris, Kiyana. "A Vaccine for Leprosy." Stanford.edu. Kiyana Harris, n.d. Web. 10 Nov. 2012. <http://www.stanford.edu/class/humbio103/ParaSites2006/Leprosy_vaccine/mlepraeantigens.htm>. "Leprosy." Human Diseases and Conditions. Advameg, 2012. Web. 10 Nov. 2012. <http://www.humanillnesses.com/InfectiousDiseases-He-My/Leprosy.html#b>. "Leprosy." New York Times [New York City] 24 Aug. 2011, Health: n. pag. Web. 10 Nov. 2012. <http://health.nytimes.com/health/guides/disease/leprosy/overview.html>. "Leprosy." World Health Organization. WHO, Sept. 2012. Web. 10 Nov. 2012. <http://www.who.int/mediacentre/factsheets/fs101/en/index.html>. "Leprosy Fact Sheet." World Health Organization. WHO Regional Office for South-East Asia, n.d. Web. 10 Nov. 2012. <http://www.searo.who.int/en/Section10/Section20/Section2293.htm>. Leprosy lesions. Microscopicblog. Underthemicroscope, 3 May 2011. Web. 10 Nov. 2012. <http://2.bp.blogspot.com/yCOTpjU08j0/TcDJpxvzOFI/AAAAAAAAAEc/gClWzlJ4M8k/s1600/leprosy.jpg>. "Leprosy patients as depicted in traditional Chinese medicine." Science Direct. Elsevier B.V., n.d. Web. 10 Nov. 2012. <http://ars.elscdn.com/content/image/1-s2.0-S0072975208021465-gr4.jpg>. Logo. World Health Organization. WHO, n.d. Web. 10 Nov. 2012. <http://www.who.int/en/>. Pfaltzgraff, Roy. "Clinical Leprosy." Stanford.edu. Stanford University, n.d. Web. 10 Nov. 2012. <http://www.stanford.edu/class/humbio103/ParaSites2006/Leprosy/snsx.htm>. "WHO blister packs of multidrug therapy (MDT) for leprosy - Rifampicin, Clofazimine, Dapsone." John's Hopkins. John's Hopkins University, n.d. Web. 10 Nov. 2012. <http://johnshopkinsghig.files.wordpress.com/2010/09/p7140241.jpg>.