A collective of health practitioners mentoring one another in topics related to nutrition. Anyone who wishes to join – You select yourself Second Monday each Month 1 - 2pm To share and build understanding of the common and uncommon knowledge of the practice of nutrition in the care and treatment of ourselves and the patients under our care. Share your knowledge with each other. Competition and knowledge hording only supports lost knowledge. This group endeavors to share knowledge and clinical experience to serve not only ourselves, but all people. “If you want to learn something read about it. If you want to understand something, write about it. If you want to Master something, teach it.” Yogi Bhajan At some point we ask you to present a topic for presentation to the group. This presentation need only be 30-35 minutes in length with a power point or notes available in Word for the group. You should be able to do a Q&A with the group to follow. Everyone will be encouraged to participate in the Q&A and it is asked that this become a roundtable type Q&A. If you chose not to present, that is your decision and you will not be ousted from the group. Push *6 now to mute your line When the speaker is finished, if you have a question or wish to add to the discussion, press *6 to be put in the queue. James Parish Atrium Health Services St Louis, MO SOT practitioner with a penchant for nutrition Logan Graduate Internship at Park County Chiropractic • Livingston, MT Packers Fan • 13-0 baby!!!! According to CDC in 2007 • 223,000 men were diagnosed with Prostate cancer • 29,000 men died from the disease African American Men are more that twice as likely as Caucasian men and five times as likely as males of Asian descent to develop prostate cancer The likelihood of developing prostate cancer increases greatly with age • Prevailing wisdom is that if you live long enough, you will likely develop prostate cancer • .1% of 30 year old males will develop prostate cancer in the next ten years. • 6.6% of 60 year old males will develop prostate cancer in the next ten years and 17% will develop it in the next 30 years. 1 in 6 men will develop prostate cancer and 1 in 36 will die from prostate cancer in their lifetime. Diagnosed with advanced prostate cancer Doctor’s told him there is no reason he should be alive Attributes it to decreasing carbohydrate load to near zero for thirty years Must hear his story Increased frequency and decrease inability to urinate Sexual Dysfunction Unremitting low back pain Pelvic discomfort Blood in Urine PSA over 4 • Controversial. Will discuss in a bit. Elevated calcium levels concomitant elevated PSA Elevated PTH • Skinner and Schwartz study with Elevated Acid Phosphatase • Significant elevation has strong correlation with metastatic prostate cancer And of course………….. Validity of PSA has come into question as of late • A study of men with PSA’s over 4, only 25% had prostate cancer. • Often after high PSA, other procedures follow Transrectal ultrasound, biopsy Some evidence biopsy increases likelihood of prostate cancer Need for better screening procedures “The Relation of Serum Parathyroid Hormone and Serum Calcium to Serum Levels of Prostate-Specific Antigen: A Population-Based Study.” • A population based study looking at the relationship between elevated PSA, PTH, and serum calcium. • Found a direct correlation between elevated PSA and elevated PTH. We already know there is a correlation between elevated serum calcium and elevated PSA levels. When calcium is elevated, we would expect to see PTH levels that are low and Calcitonin levels that are high….This doesn’t seem to be the case Instead what we find is that when PSA and calcium is elevated, so is PTH. Explanations? • Hyperparathyroidism may help to explain this phenomenon. • Increased PTH due to failure of calcium sensing cells in the parathyroid cause increased levels of calcium in bloodstream So a possible explanation for this finding is that a hyper parathryroid gland is at least implicated in prostate disease. Some questions that come to mind • Are calcitonin levels elevated at the same time as PTH in these cases- One could reasonably expect that to be the case • Is prostate disease, in part, caused by hyperparathyroidism, sub clinical or pathological? • Is there a mechanism for prostate to signal the need for tissue calcium to parathyroid? i.e. is prostate driving “hyperparathyroidism” (thanks Steve) • Thoughts in the discussion Tomato • Much has been made of the benefits of lycopene in the prevention of prostate cancer. But is it the lycopene? • One study found that there was no difference in rates of cancer among rats that were fed lycopene supplements. • However, the rats in the study that were fed tomato powder has significantly lower incidence of prostate cancer…Why? As if we didn’t know. • Boileau TW, Liao Z, Kim S, et al. Prostate carcinogenesis in N-methyl-Nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. J Natl Cancer Inst. 2003; 95:1578-1586. Saw Palmetto has been used as a herbal therapy for many years •The liposterolic fatty acid levels in Saw Palmetto (LESP) are the compounds around which most of the research has revolved. •Evidence is abundant of Saw Palmetto’s ability to decrease urinary symptoms in BPH sufferers Much of the research has focused on the inhibition of 5-alpha reductase as a mechanism of action for Saw Palmetto • Research has been mixed as to the level of effectiveness on 5-alpha reductase. Other research focused on the possibility of LESP blocking the formation of Leukotriene B4 and Prostaglandin E2. • One study found LESP to be an effective lipooxygenase inhibitor, thus reducing the proinflammatory Leukotriene B4 Stinging Nettle (Urtica Dioica) has been extensively studied in the treatment of cases of BPH. • Focus initially was on the role as a 5-alpha reductase inhibitor in the body. • More recent research is focusing on the ability of 9-hydroxy-10-trans-12-cis-octadecadienic acid (HOA) to act as an aromatase inhibitor. First one to say of 9-hydroxy-10-trans-12-cisoctadecadienic acid 5 times fast wins a bottle of Prost-X!!! (Legal Disclaimer: This is not a real offer.) Increased estrogen levels in men is positively correlated with increases in BPH Aromatase is an enzyme responsible for the conversion of androgens into estrogens. • Testosterone Estradiol • Androstenedione Estrone HOA blocks the action of Aromatase as a means of reducing estrogen concentrations in the body. Palmettoplex is the perfect support for the prostate gland. • • • • Saw Palmetto Stinging Nettle Tomato Powder Bovine Prostate PMG™ This is a great prophylactic or therapeutic product • 1-2 TID Problem: Too much calcium in the bloodstream • Two main stores of calcium: The tissues and the bones. We gotta put this stuff somewhere! As before, we know serum calcium has a correlation with high PSA and prostate dysfunction and disease - reduce the calcium floating around Prost-X™ and Cataplex F Cataplex F • Vitamin D and Vitamin F work in synergy. • D brings the calcium through the gut and into the blood. F takes it out of the blood and puts it in the tissue i.e. prostate. Prost-X A rich source of phosphatase, Prost-X allows for proper calcium assimilation and transport of calcium into bone. Also helps to drive calcium back into the prostate for utilization. Reducing BPH. Cataplex 2-3 TID F Prost-X 1-2 TID Prosta-Co • Contains Saw Palmetto and Stinging Nettle in greater concentrations compared to Palmettoplex Equivilent of 1070 mg vs. 320 mg of Saw Palmetto Equivilent of 666 mg vs. 220 mg of Stinging Nettle • Also contains Pumpkin seed oil and Crataeva stem bark Cranberry Complex to prevent Urinary tract infections Gut Flora Complex if Candida becomes a problem And of course Immuplex, Thymex, Andrographis Complex, and Echinacea Premium for up-regulation of immune system. Dr. James Parish • Atrium Health Services • St. Louis, MO • (314) 872-9955 And GO PACKERS!!!!!!!! 16-0 BABY!!!!!!!