Gen-Probe, Tigris DTS

Report
Robin A. Felder, PhD
The University of Virginia
Department of Pathology
TRANSFORMING HEALTHCARE
THROUGH INNOVATION
Disclosures
 University of Virginia
 Department of
Pathology
 Medical Robotics
 Medical Automation
 Hypogen
 WellAWARE Systems
 MeyeChem
 Proteus Bio
 Global Cell Solutions
 Monte Piccolo Farm
Pursuit of Wellness
 State of complete
physical, mental and
social well-being
 Health results from
primarily positive
perspectives and choices
by which to live
 Technology can provide
information that facilitates
positive choices
Physical
Social
6.2
9.1
8.0
Cognitive
Wellness Balance
© Felder, 2011
Wellness Support
 Growing need for new sources of
data, and data interpretation
 Integration of multiple diagnostic
sources (lifestyle, self testing)
 Integrated wellness and health
record
 Ongoing information support for
maintaining healthy lifestyles
Wellness Technologies Monitor
 Nutrition
 Exercise
 Biometrics
 Pain reduction
 Stress reduction
 Sleep improvement
 Mood enhancement
 Health and wellness
Wellness Support
 Food coaching
 Rewards
 Exercise
 Nutrition
 Therapeutic compliance
 Consequence reporting
 Consequence forecasting
Overcome vicarious
goal fulfillment or,
“exhaustion of selfcontrol”
Home Health IT
 New revenue sources:
Medical Cloud
coaching and
Interpretations
Cloud
Interpretations
Proliferation
of Wellness
Tools
 Accelerometer
based
Striiv
Basis
FitBit
 Various models
for data delivery
 Basic
physiologic
measurements
Shine Misfit
BodyMedia
Nike Feulband
Scanadu
Tricorder
Zephyr
Information Week
BodyMedia
KNOWS
LEARNS
You and what is
around you
What you like
SENSING
Local content
& services discovery
Source: Jarrin (Qualcomm)
DISCOVERS
Things relevant
to you
FILTERS
Out the irrelevant
SEEING
INTERACTING
Augmented reality UI:
Map, 3D, in building
navigation
Connection manager
(WAN, Wi-Fi)
KNOWS
LEARNS
You and what is
around you
What you like
SENSING
Local content
& services discovery
Source: Jarrin (Qualcomm)
DISCOVERS
Things relevant
to you
FILTERS
Out the irrelevant
SEEING
INTERACTING
Augmented reality UI:
Map, 3D, in building
navigation
Connection manager
(WAN, Wi-Fi)
Lifewatch AG
new ipad mini
Portable Diagnostics
 iPhone based




portable ultrasound
EKG
Otoscope
Dermatoscope
Microscope
Cell Scope ™
 Dermatoscope – iPhone clipon
 Transmits high quality magified
pictures of skin blemishes
 “Smart Otoscope” – iPhone
ear drum microscope
 Transmits pictures of videos of
the ear canal and ear drum
 Looks at progression or
regression of disease
Otoscope Images
Normal Ear Drum
Ear Infection
Ruptured ear drum
Cloud Based Diagnosis of Parkinsons
 Non-invasive phone
 Low Cost
based
 Accurate (98%)
 Remote, non-expert
 Rapid diagnosis
 Scalable to large
populations
Max Little - Parkinson’s
Voice Initiative
TED Conference 2012
iPhone Body Fluid Diagnostics
 Biosense Technologies
 uCheck
 ToucHb
Continuous Glucose Monitoring
Dexcom
Embedded Wellness Sensors
 Instrument common
fixtures
 Wireless
transmission of data
 Web based
aggregation and
interpretation
Action Inspired Instruction
 Real time coaching
 Medically approved
content
 Tailored for individual
Passive Wellness Monitoring
Healthcare providers
Vital Sensor
Urine analyzer
Data management PC
Urine protein
Urine glucose
·Body temperature
·Pulse
·Blood Pressure
·Body fat percentage
The M.A.R.C. In-Home
Health Monitoring Project
 Create a model where the impact of chronic
disease is delayed or avoided
 Provide opportunity for medical intervention
before a crisis occurs
 Minimize impact of chronic disease on the
healthcare system
Passive Remote Sensing
 Wireless Sensor Array (WSA) – gathers data on daily
activities
 Data Manager (DM) –transmits data to data analysis
servers
 Capture Analysis & Reporting Engine (CARE) – captures
potential problems and alerts caregiver
Passive Gait Sensors
Vibration
sensors placed
in the house
detect occupant
gait
Passive Physiologic Sensors
Physiologic
sensors
embedded in
common
household
furniture and
fixtures
Sleep Monitoring
 Sleep apnea affects more
than 40 million people in the
United States alone of which
85% are currently
undiagnosed
 sleep apnea testing and
therapy market that is
expected to reach more that
$4 billion by 2012
Passive Vital Sign Bed Monitor
Mattress pad to measure:
• Sleep quality
• Pulse (and HRV)
• Breathing
• Movement/
restlessness
• Bed exit
• Subject position/
turning
• Body temperature
• Blood Pressure
Passive Sensing
Polysomnography
Sleep Quality Graphs
Restful Resident
Restless Resident
Remote Automated Triage
 Real time assessment of participant health
status/well being
 Ability to drill down to specifics
 Built in automated optimized dispatching
 Manual override of dispatch event or
downstream processes
30
One Click Trending
 Health
 Socialization
 System
utilization
Telehome Monitoring Decreases
Costs by 74%
70000
60000
Dollars $
50000
40000
30000
20000
10000
Overall Cost of Care Comparison
$67,757.88
Unmonitored
80000
$17,407.02
Monitored
0
N=21 in each group, P<0.05;
Telemed J E Health, 2007 13(3):279-85
FUTURE WELLNESS
TECHNOLOGIES
3D Manufacturing
36
Wearable Cancer Detection
 First Warning Systems™ heat distribution sensing
sports bra
0.2cm
1cm
4cm
Underwear That Measures Blood
Pressure
 Pulse wave velocity
correlates with blood
pressure
 Tissue impedance shows
passing pulses
 Pulse timing correlated
with relative pressure
 Continuous blood
pressure monitoring
Automated Pharmaceuticals
 Automated Pill – iPill (Philips)
 Magnatrace™ System looks for pill
ingestion
 Networked pills (Proteus
Biomedical)
 Instrumented Pills
 Cost < $0.01
 Measure and send physiologic signals
through body electrically
 Receiver is a patch worn on the body
that also logs respiration, heart rate and
body movement, sleep patterns
Automated Intestinal Biopsies
 Intestinal diagnostic
imaging coupled with
miniaturized biopsies
 Pillcams with
intestinal “Velcro” to
arrest the camera at
a selective location
 Continuous
monitoring
MIT Technology Lab
The Eye as the Window to Health
Medical Robotics
UCSD
Preventive Science Inc.
Univ. of MD, Baltimore
MeyeChem, LLC
 Real time glucose
monitoring
 Alerts for low or high
glucose concentrations
 Trending analysis
 Food coaching via
telenutritionalmentoring
Virtual Reality
 Image enhancement,
correction, zoom
 Correction currently
limited to 0.2
logMAR, 20/32
 Full view software
modulated images
 Superimposed
augmented reality
Off axis projection with
transflective diffuser 90° field
eyewear iOptik
Gas-permeable
nanopolarizer
(iOptik contact
lens)
Diopter adjustable
mini-scleral lens
and wearable
computer (iOptik)
Zoom lens (3X)
UCSD
Augmented Reality
 Projection of
underlying anatomy
on living tissue
 Relies on
superimposition of
reality and
previously scanned
animated image/data
Not for the Faint Hearted
Receptivity
 Presenting health vs
wellness to a patient
 Determining what
information is TMI
 Optimizing the time
for the presentation
of wellness strategies
“Wellformation”
Medical Automation.org
A non-profit
educational
organization
improving
healthcare quality
and efficiency
through teaching
automation
principles and
their application in
health systems
http://medicalautomation.org
TagLine - Medical reality
http://medicalautomation.org
Robotic Reality
HRP-4C National Institute of
Advanced Industrial Science and
Technology

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