Ideas for GK-12 and Rocky Mountain High School Carol Seemueller and Katherine Kiwimagi Big Picture Outline Anatomy and Physiology Lessons New/Enhanced LabQuest labs Bioinformatics/Tissue unit Kinesthetic Activity/NMJ Biology Beetle Project (early detection) Introduce LabQuest AP Biology (next semester) Collaboration with Slovenia (Phages and Bioinformatics) Micro lessons that incorporate visualization software of molecular interactions Regulation of cell cycle Game/activity Short presentation of current research involving regulation factors Anatomy and Physiology: Lab Quest Micro Lessons Objective: Emphasizing the connection between math, technology and human physiology Our Plan: Develop micro lessons that integrate these concepts 1) 2) Grip strength lab (student write a hypothesis for muscle fatigue --- go to literature we provide to see what scientists today think) Skin temperature lab (micro lesson that connects rate to slope using students collected data) http://upload.wikimedia.org/wikipedia/commons/4/46/DNA_Repair.jpg Anatomy and Physiology: Introduce Bioinformatics Objective: Introduce bioinformatics while studying tissues Our Plan: Find a Clinical Study related to a tissue defect caused by genetics Develop a lesson that has students use bioinformatics software such as BLAST to help solve or better understand the Clinical Case Anatomy and Physiology: Model a Neural Muscular Junction Objective: Students will increase their understanding of the neuromuscular junction through a kinesthetic activity. Our Plan: Introduce the Neuromuscular Junction Students will build a model of the neuromuscular junction that reflects the relationship between form, function, and cell communication Anatomy and Physiology: Develop a VO2 max lab using lab quest Objective: To develop a new VO2 max lab for the LabQuest technology To have students apply their knowledge of math to the data they collect Our Plan: Find a contact in the Exercise and Sports Science Department at CSU that would give a tour to students and talk about VO2 max Develop lab that has student calculate their own VO2 max Anatomy and Physiology: Expand on the students understanding of Bioinfomatics Objective: Using bioinformatics software, connect the dots between DNA and Cell signaling Our Plan: Find a Clinical Study related to a cell signaling defect caused by genetics (Cystic Fibrosis / Asthma…) Develop a Micro lesson that has students use bioinformatics software such as BLAST to help solve and better understand the Clinical Case Anatomy and Physiology: Other Ideas Possible collaboration about testing the characteristics of Bone Design an EMG controlled Device Biology: Beetle Project Objectives: “connect To the dots” relating rates of infestation “math to ecology” see the interdependence of science Math, State Engineering, Chemistry, Biology standards #2 and #9 Introduce the Niche concept Brief introduction of Evolution (golden toad article extinction/adaptation) Application Experiment of the scientific method design, Data analysis and Presentation Biology: Beetle Project Our Plan: Have Students Design or do one of the following things 1. An Early Detection system (to detect beetles early) 2. 3. (or) An experiment that validates current methods of detection Present opposing opinions on beetle kill (Research Lead Discussion) Biology: Beetle Project Project idea Early Detection System Introduce students to Beetle life cycle Properties of the blue fungus Current methods of detection and prevention Article about Global warming (Pine Bark Beetles Affecting More than Forests: air quality and weather) –NSF- Create a hypothesis Design an experiment Discuss results of experiment Present to the class Biology: Beetle Project Project idea Test Current Methods Help student Design experiments that would test current method Few current methods Pheromone packets Spraying techniques up to four inches Electronic Kit noise Slash and burn methods http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg Example Student Idea Biology: Beetle Project Project idea Ideas that student could come up with on their own Hypothesis: Placing pheromone packet on tree will send beetles to trees next to it. Infected wood would be more acidic than noninfected wood. Beetles favor lodgepole due to the resistance other trees have to pine beetles http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg Example Student Idea Biology: Beetle Project Project idea Ideas that student could come up with on their own Material and Methods Observe current trees with patches and without patches (quantify) Build a wood crushing and dissolving kit. Use a pH indicator to see if one sample is more acidic than the other Identify different species of trees and graph vs presence of infection http://www.estesparknews.com/wp content/uploads/2008/04/pitchtubes.jpg Student comparison of cause Biology: Beetle Project Project idea Human impact vs. natural cycle Students conduct research Students present research Student discuss research with peers Biology: Beetle Project 1 Week Plan Discussions and small readings Beginning of week Discuss the concept a niche Read about extinction and the interdependence of species on one another Introduction to Experimental Design Introduction to Project Design Biology: Beetle Project 1 Week Plan Students Draw Up Proposal Middle of week Give students time and help to develop a beginning to end research proposal Break Build it up or all together and test their apparatus Biology: Beetle Project 1 Week Plan End of week Students Present to the class their findings Help student develop presentation Let student present to the class Biology: Introduce Lab Quest What is LabQuest? Objective: Introduce the connection between math, technology, and biology in a 9th grade Biology classroom. Our Plan: Develop micro lessons that introduce and integrate these concepts Use micro lesson in classroom Biology: More Ideas Design Bug catchers (pitfall traps) for current Ecology lab Learn how to design and work with limited materials Model animal movement/migration (Monarch Watch) Add GPS sensor to prairie ecology project and relate to size/scale of student drawn maps AP Biology: Slovenia, Phages and Bioinformatics Objectives: Expose students to international connections Introduce and use Bioinformatic software Our Plan Design a parallel experiment with the students from Slovenia that involves isolating soil bacteriophages AP Biology: Visualization Software and Molecular Interactions Objective: Introduce concepts of bioinformatics while teaching molecular interactions Our Plan: Design lesson and lab that incorporate the use of bioinformatics software GLI1 Promotes CDK4ofActivation? AP Biology: Regulation Cell Cycle Objectives: Connect concepts learned in class to research currently being conducted To create lessons that make the complex cellular interaction inspiring and memorable for the students Our Plan Have the fellow or a guest give a simplified research proposal presentation Design a game or activity that relates to cell cycle regulation GLI1 Promotes CDK4 Team Activation? Science Olympiad Rocky Mountain has a Science Olympiad team which must complete several building events for competition (robotics, bottle rockets, egg carrying devices, bridges/towers) Summary Anatomy and Physiology Lessons New/Enhanced LabQuest labs Bioinformatics/Tissue Unit Kinesthetic Activity/NMJ Biology Beetle Project (early detection) Introduce LabQuest AP Biology (next semester) Collaboration with Slovenia (Phages and Bioinformatics) Micro lessons that incorporate visualization software of molecular interactions Regulation of cell cycle Game/activity Short presentation of current research involving regulation factors Questions?