Enzymes

Report
Materials: 3 worksheets
• Catalyst (5 min):
1. How did temperature affect the rate of a
reaction as seen in our Gizmo?
2. What are 2 ways enzymes can be denatured?
Materials: 2 half sheets and paper
from yesterday
• Catalyst:
Identify the enzyme, substrate, and products in the
following sentence.
A triglyceride is broken down into glycerol and
fatty acids by lipase.
Elite Eight Trait Check-Up
1. Respect the Threshold
1. Everyone on time?
2. Silent for First Five?
2. Be Prepared (2 min)
1. Seated
2. Have materials
3. Working on catalyst
Unit 1 Class Point Challenge
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Period 1:
Period 2:
Period 4:
Period 5:
Period 6:
Period 7:
.77
.88
.90
1.28 Winners!!!
.37
.76
Class Motto
If there is a problem,
We look for a solution.
If there is a better way,
We find it.
If we need help,
We ask.
If a teammate needs help,
We give.
Announcements
• We will be talking about Science and
Engineering Expo Projects on Thursday/Friday.
Come with research question (I have some of
yours)
• Enzymes Quiz Tomorrow
• Enzymes project due
– Thursday: Periods 1, 2, 4, 6
– Friday: Periods 5, 7
Standard
• SB1b. Explain how enzymes function as
catalysts.
Recap
• Catalysts speed up chemical reactions.
• Enzymes are catalysts in living things.
• Catalysts and enzymes work by lowering the
activation energy necessary for a reaction to
occur.
EA is lowered by the enzyme
How are enzymes denatured?
• Denatured = Destroyed
• Enzymes are denatured by high temperatures
and low pH (acids)
Collision Theory Gizmo
• How did temperature affect the speed of
molecules in the Gizmo?
• How would this change the reaction?
So how would adding a catalyst affect
the reaction?
• Would it affect the speed of the molecules?
• Would it affect the speed of the reaction?
Objectives
• I can explain what it means for an enzyme to
be specific, unchanged, and reusable.
• I can recall the two ways enzymes are
denatured.
• I can identify the parts of an enzyme/substrate
complex.
• I can summarize the importance of enzymes in
living organisms.
Notes 2.3: Enzymes and Catalysts
• This is a continuation from last week! You
may write on the same notes paper.
Enzymes
Substrate: the material that an enzyme
binds to
Enzyme-Substrate Complex: enzyme and
substrate together
Active site: location where the substrate
binds on the enzyme
Enzymes
• Enzymes often end in “ase”
– Lactase (breaks down lactose)
– Helicase (unzips DNA)
– Amylase (breaks down amylose)
– Lipase (breaks down lipids)
Enzymes (Think – Pair – Share)
• What’s a substrate?
• What do enzymes usually end in?
• Is lactase an enzyme or a substrate? How do
you know?
• What do you predict is the substrate for the
enzyme sucrase?
Characteristics of Enzymes
• Enzymes are:
–Specific
–Unchanged in a reaction
–Reusable
Characteristics of Enzymes
Enzymes are specific:
• They only work with one reaction
• The enzyme and the substrate fit together like
a lock and a key
Video
• Think: How does this game show related to
the characteristics of enzymes?
Characteristics of Enzymes
Or you might see it like this…
• You will have to be
ready to read a
variety of different
diagrams
Enzymes (Think – Pair – Share)
• What is an enzyme?
• What does it mean to say that enzymes are specific?
• What does it mean to say that enzymes are
reusable?
• Why are enzymes important?
Enzymes
What is structure X?
What is structure Y?
What is structure Z?
Enzyme Disorders
*LEL (Low Enzyme Levels) is America's & the world’s number one
cause of sickness and death.
*Inhibitors are molecules that decrease enzyme activity, and activators
are molecules that increase activity. Drugs and poisons are often
enzyme inhibitors.
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Cystic Fibrosis
Gaucher's Disease
Low Stomach Acid
Inflammatory Bowel
Disease/Syndrome
• Intestinal Inflammation
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Ulcerative Colitis
Ulcers
Acne
Gingivitis
Sprue
Pancreatic Insufficiency
Classwork 2.3: Enzymes
• You will have 15 minutes to work on this
assignment.
• Graded for accuracy!
Enzymes Project
Objective: Manipulate enzyme cut outs to
represent a chemical reaction in our body.
Directions: 2 people at each table start with
part A and 2 people start cutting. Then switch!
Panther Pass
1. What do enzymes do?
2. What does it mean to say that enzymes are
“specific”?
3. What are the 2 ways enzymes are denatured?
4. Which of the following statements best describes
enzymes?
a)
Enzymes cannot be reused after a reaction
b)
Enzymes are organic catalysts
c)
Enzymes slow down chemical reactions
d)
Enzymes can bind to any substrate

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