I´ve worked on it for more than 10 years Prof. Dr. med. G.L. Floersheim Dermatologist Basle – CH In co-operation with Dr. med. L. Gilli Dermatological Clinic University Basle - CH Prof. Dr. med. M. Oberholzer Institute of Pathology University Basle - CH How do wrinkles occur ? Is the cause Influenceable? Please follow me The visible skin is made out of the same material as hair and nails: KERATIN is produced by specific cells in the lower skin layers as hardened squamous cells create the visible skin cells in the lower skin layer can‘t produce keratin without BIOTIN 70 mcg Biotin Are needed daily for proper skin cell division food sources are milk, liver, kidney, soybeans, fruit, rice and vegetables leads to thinner, dry, pale skin with wrinkles – the typical symptoms of aging skin is caused by wrong foods, malabsorption and other metabolic disturbances, intestinal diseases, dieting etc. Please follow me into a dangerous world terrorists ? environmentalists ? escaped prisoners ? are especially hidden in the ultraviolet solar radiation 100 billion cigarette smoke free radicals per inhalation drugs, smog, ozone etc… are highly aggressive molecules which cause accelerated cellular oxidation in the body destroy the normal skin conditions and leaves the skin vulnerable to the environment destroy the specific Keratin-forming cells leave the skin damaged - the skin appears dull and old before it‘s time Both woman are 48 years old Please follow me into the world of cosmetics use chemical skin peel with - alphahydroxy acid (AHA) - Tretinoin (generic Retin-A) - Trichloroacetic acid (TCA) these chemicals damage the skin surface which produce abnormally accelerated cell division rates resulting in less wrinkling These chemical applications require repeated treaments which leads to permanently thinner, sensitive and damaged skin also use muscle paralyzing injections with the very commonly used and widely misunderstood - Botox toxin Botox relaxes the muscles therefore temporarily diminishing the lines in the skin - it`s toxic (long term) - it can`t be used in areas lower than the eyes - it can reduce or eliminate the movement in the treated area use growth factors and hormones - ACTH - thyrotropin - luteinizing hormone (LH) - human growth hormone (HGH) can switch skin cells into higher gear making them produce more collagen which store more water in the upper layer multiple side effects in long term use can include - diabetes - pooling of fluid - high blood pressure - heart failure use - Collagen injections - Collagen is injected under the wrinkles and it pushes the wrinkles up making them less visible - as a foreign protein the injected collagen will be attacked by the immune system which may lead to serious allergic reaction and carry risk of triggering a long lasting autoimmune disease use creams, gels, liquids - moisturizers - oil in water emulsions hydrates and improves water retention in the epidermis, particularly in the surface of the skin - daily treatments boost the inability of the skin to store and keep water - doesn`t reach deeper layers use a comprehensive approach to treat the cause into my world of dermatological science are the regular process of aging are hereditary and determine the number of cell divisions The genetic code gives the order to start the biological aging process of the skin aproximately at the 25th year of life. With less amounts of Biotin, the cell division rate is reduced and the aging process increases Also included in the aging process: The blood flow through the skin, the fatty tissue in the hypodermis and the ability to store humidity is reduced. can stop this regular process of aging delay the process and minimize the signs of aging skin we can improve the number of cell divisions with specific doses and application of biotin - even if the genetic code gave the order to decline. We can reduce the terrible influence of free radicals with our specific combination, dosage and application of antioxidants drastically. We can feed the higher rate of healthy collagen and elastic fibers with our specific oil-in-water emulsion and keep their ability to stay supple and plump for youthful appearance and elasticity of the skin. ® - all active substances are formulated in scientifically proven doses - Cream for topical application - Capsules for oral application is the only one - with a guarantee for the comprehensive treatment of wrinkles from inside and out of biotin - improves the keratin production of biotin - gives better appearance to the highly active epidermis (skin surface) of antioxidants works as a shield against free radicals - on the skin surface - in the body of antioxidants in the emulsion + capsules works externally and internally and improves the ability of the outer most skin layer to store water for a supplet and emollient youthful appearance with improved elasticity of the skin of the specific oil-inwater-emulsion formula nutrifies the already improved collagen in the upper skin layer (dermis), improve the hydration ability and pushes up the groove of wrinkles of biotin plus antioxidants plus oil-in-water-emulsion in a specific formulated vehicle assures success in wrinkle reduction over long periods of Lift Complex® Is proven in clinical studies Study: 30 test subjects aged between 64 and 90 years with wrinkles on the forearm. Results: Due to the treatment with Lift Complex® Tab. 1: Comparison of wrinkling above dorsal forearm and hand before and after the treatment with LIFT COMPLEX (biotin 0,25%) by Dermasthetik group B C A N 8 10 10 treatment placebo biotin 0,25 % biotin 0,5 % wrinkling at the end of treatments as compared to beginning decreased % (no of comparisons/ total comparisons) equal % (no of comparisons/ total comparisons)) encreased % (no of comparisons/ total comparisons) 10/32 24/40* 14/40 18/32 14/40 22/40 4/32 2/40 4/40 31 60 35 56 35 55 *p<0.02 - fine lines were noticeably diminished - wrinkles decrease up to 60% - age spots were noticeably lighter 13 5 10 Subjects: More than 300 test subjects with age ranges between 31 and 68 years with typical wrinkles characteristic of accelerated aging in the face. All of the subjects reported prior use of different preparations without satisfactory results. Results: The results after using Lift Complex consistently (3-6 month period) confirm the results of the study in the Basle dermatological clinic. After five years neither the doctors nor the patients could see the signs of accelerated skin aging as they saw before. The treatment with Lift Complex® is proven in clinically studies - without any side effects ! The treatment with Lift Complex® - Is more effective with a shorter period of application as with tretinoin – the former predominant pharmaceutical therapy to influence wrinkles of Lift Complex® was a secret during the research, the development, and the studies ® - has revealed all those secrets and is actually known as the only clinically proven treatment from inside and out which works successfully without side effects ® - serves and satisfies people today in many different countries with the only available comprehensive and proven successful antiaging treatment which works from inside and out of Lift Complex® I´m proud to work on it for more than ten years – and I love to continue because I like to make sure: Beautiful, healthy skin is no accident!