Slajd 1

Report
BIOMATERIALS
J. Dutkiewicz
Institute of Metallurgy and Materials Science of the Polish
Academy of Sciences
Źródło: Kay C Dee, David A. Puleo, Rena Bizios: An introduction to tissue-biomaterial
Biomaterial– a substance other than medicament manufactured from
interactions,
John Wiley components
and Sons, New which
Jersey, 2002
natural or synthetic
is intended to substitute organ or
tissue or part of it to take over its function.
Biomaterials industry
year 1987
4,7 mld $
Natural materials
5,7 %
Polymers
47,1 %
Year 2002
11,7 mld $
Composites
18 %
Metals
44,5 %
Materials
Natural
6,3 %
Metals
29,9 %
Polymers
42,8 %
Composites
0,0 %
Ceramics
2,8 %
Ceramics
2,9 %
Polarization resistence (Ω/cm2)
9
Safe only for certain
period
8
Stopy Ti
CoCrNiMo
Stal AISI 316L
7
Toxic
6
Neutral
5
4
3
Biotolerance
Corrosion resistence w zależności in relation of tissue reaction for various materials
Kość i zastąpienie kości
Metallic Biomaterials in reconstruction surgery

steels Cr-Ni-Mo

alloys Co-Cr-Mo, Co-Ni-Cr-Mo, Co-Cr-Ni-Mo-Fe

Ti i jego stopy: Ti-6Al-4V, Ti-6Al-(4-9)Nb,
Ti-6Al-(3-6)Nb-(1-6)Ta, Ti-12Mo-6Zr-2Fe, Ti-15Mo-3Nb,
Ti-15Mo-5Zr-3Al, Ti-Zr-4Nb-2Ta-0,2Pd,
Ti-15Sn-4Nb-2Ta-0,2Pd, Ti-13Nb-13Zr,

Ni-Ti shape memory alloys

alloys Nb i Ta

Noble metals Au, Ag, Pd
Mechanical poroperties of titanium
Examles of application of titanium in surgery
Płytka rekonstrukcyjna
blokowana
Płytka ramienna
blokowana
Płytki szyjne
Examples of application of Ti6Al4V in surgery
Implanty zastępujące krążki
międzykręgowe „Cage”
Śruby transpedikularne do
stabilizacji kręgosłupa
Implanty zastępujące kręgi
X-ray image of back bone with avisible
shift of vertebras , causing oppress on
nerves and pain of the pacient..
Operation is based on stiffening of
vertebras with titanium support
constructiion regulating distance of
vertebras eliminating oppression of
nerves.
Dental Implants &
Coated / uncoated
Superstructures
Nitinol
• NIckel-TItaniumat composition 50 :50 with a possible
application of superelasticity in dental
orthodontic medicine
Predetermined
Shape of matrix
Orthodontic Applications
“Stents”
Bioneutral ceramic materials
In stomatological practice
Monolitic ceramics base on Al2O3
-Al2O3:
• bioneutral material
• minimal
chemical changes in
contact with tissue and organism
fluids
• brittless and low toughness
(improvement possible by additions of
1 m; ZrO2 [4])
Typical bioceramic elements: alumina
dental implants of cerasiv GmbH
"Dyract® AP offers the restorative
potential to fulfil most applications of
traditional glass ionomer restorative
and composite resins .. "
Compomers
cavities
etch
adhesive
compomer placed
setting
http://www.dentsply.co.uk/articles/018.htm
Bio-active ceramic materials
:
 bioglasses sodium-calcium (Na2O-CaO-SiO2-P2O5) [8]
 sintered hydroxyapatite (Ca10(PO4)6(OH)2) [9,10]
 -calcium phosphite(Ca3(PO4)2) [11]
 two phase ceramic hydroksyapatite-calcium phosphate
 crystalline oxyfluoroapatite (Ca10(PO4)6(O,F2)
 vollastonite (CaO.SiO2) in a glass matrixMgO-CaO-SiO2 [13]
Due to a poor mechanical properties of hydroxyapatite, most popular are
layers on ceramic or metallic substratres
Apatite
Ca5X(PO4)3
X = F, Cl, OH
hexagonal, rod like crystals,
Colour: colorless, sometimes
yellow, blue, red
shiny
Rysa: biała
Hardness : 5,0 – in Mohs
scale
density: 3,16 - 3,22 g cm-3
Root Canal Sealers
Materials from cements to resins have been used
 biocompatible
 antiseptic
 non-soluble
 adhesive
 slow setting
 radiopaque
 dimensionally stable
 removable if required
 achieves a good seal
Cytotoxic & tissue irritating potency:
• Zinc oxide – eugenol in longest use
• Epoxy resin based
• Sealers containing a small % of
paraformaldehyde to kill bacteria & fix
remaining pulp tissue.
Biocompatible alternatives:
4) Calcium hydroxide based to promote
tissue repair at the apex.
5) Mineral trioxide aggregate (MTA)

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