Pre-Krebs and Krebs Cycle

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Pre-Krebs and Krebs Cycle
• Take place in the mitochondria
• 2 pyruvate molecules enter the mitochondria
from the cytoplasm
• 3 Functions:
1. Produces NADH and FADH2
2. Produces ATP
3. Produces oxaloacetate
Pre-Krebs
1. Pyruvate enters the
mitochondria from the
cytoplasm
2. CO2 is removed from
pyruvate and Acetyl
CoA is formed
• NAD+ is converted to
NADH
• Krebs Cycle (Citric Acid)
• 3. Acetyl CoA attaches
to oxaleacetate creating
citrate
• 4. Citrate breaks down
into intermediates,
releasing CO2
• 4. NADH is produced
• 5. ATP is formed
• 6. FADH2 is produced
• 7. Oxaloacetate is
regenerated and
continues in the Citric
Acid Cycle.

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