Scientific Description

Report
Epidermodysplasia Verruciformis
By: Hannah Howe
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*Scientific Description
*Epidermodysplasia Verruciformis, or EV, is a
rare skin disorder that exposes patients to
the human papillomavirus (HPV) and
cutaneous squamous cell carcinomas. The
disease is linked to chronic infection of HPV.
Skin eruptions of flat-to-papillomatous,
wartlike lesions and reddish-brown
pigmented plaques on the trunk, the hands,
the upper and lower extremities, and the
face. Malignant skin tumors (carcinomas),
usually squamous cell carcinoma, develop on
the patient with this disease.
*Description
*This disease
causes warts and
horns to form on
the trunk, hands,
feet, and face.
They form due to
exposure to the
human
papillomavirus.
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*Symptoms
*Flat verrucous warts
*Skin bumps on back of
hand
*Flattened warty skin
lesions
*Increased vulnerability
to human
papillomaviruses of the
skin
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l=en&sa=X&gbv=2&biw=1366&bih=613&tbm=isch&tbnid=H
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120&ty=130&page=1&tbnh=127&tbnw=178&start=0&ndsp
=20&ved=1t:429,r:3,s:0
*Causes
*Doctors have linked genetics to
Epidermodysplasia Verruciformis.
Although this disease is rare, doctors say
the person inherits the disease from their
parents or it “runs” in the family.
Another major cause of this disease is a
horrible immune system. This disease is
found in countries that don’t have the
best of medical care.
*Cure for EV
*There is no cure for Epidermodysplasia
Verruciformis.
*People diagnosed with this disease can:
-have surgeons remove the warts, but need to
be aware that the warts may go back
-try chemotherapy and other drugs prescribed
by a doctor
-one case was treated with a combination of
acitretin and interferon alfa-2a
*Worst Case Scenario
*The worst case scenario
Before Surgery
After Surgery
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w=1366&bih=613&tbm=isch&tbnid=bqF5H3N5BXlgvM:&imgrefu
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sALuyHFAQ&zoom=1&iact=hc&vpx=941&vpy=149&dur=2183&hovh=1
92&hovw=256&tx=150&ty=114&page=2&tbnh=121&tbnw=151&
start=22&ndsp=22&ved=1t:429,r:6,s:22
for EV is that you are
not able to use your
hands or feet.
Depending on how bad
the case is the hands
and feet can become
very heavy and
uncomfortable due to
the warts. In Treeman’s
case, he will need two
surgeries every year to
keep them from growing
big again.
*FACTS
* Epidermodysplasia Verruciformis effects less than 1,000
people in the United States.
* This disease can be linked to the mapping of chromosome
17.
* EV is usually diagnosed when the patient is between the
ages of 1 and 20.
* EV is more commonly found in countries with little medical
treatment available.
*
* http://emedicine.medscape.com/article/1131981overview
* http://www.rightdiagnosis.com/medical/epidermodyspl
asia_verruciformis.htm
* http://www.ncbi.nlm.nih.gov/pubmed/11464195
* Information was also pulled from the documentary
Treeman: Search for the Cure that I found on youtube

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